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Draft:Martin Ugander

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Martin Ugander
MD PhD
Born
Martin Ugander

1975 (1975) (age 50)
Stockholm, Sweden
NationalitySwedish
Alma materLund University
Scientific career
FieldsCardiology
Clinical physiology
Medicine
InstitutionsLund University
National Institutes of Health
Karolinska Institutet
University of Sydney
ThesisDysfunctional but viable myocardium - ischemic heart disease assessed by magnetic resonance imaging and single photon emission computed tomography (2006)

Martin Ugander (born 1975) is a Swedish medical doctor, research scientist, inventor, entrepreneur, and Professor of Cardiac imaging at the University of Sydney, Australia, best known for his work on cardiac magnetic resonance imaging (MRI), electrocardiography (ECG), and cardiac pumping physiology.

Early life and education

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Born in Sweden, he grew up in Woodcliff Lake, New Jersey, USA, where he graduated from Pascack Hills High School in Montvale, NJ, USA. He undertook one year of undergraduate studies at McGill University, Montreal, Canada, before enrolling in Lund University, Sweden, graduating with an MD in 2001 and PhD in 2006.[1][2][3][4]

Career

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During medical school at Lund University he served as President of the Medical Students’ Association 1996-1997. While at Lund University he was part of the team that determined aspects of cardiac mechanics including the role of the motion of the atrioventricular (AV) plane in cardiac pumping, also referred to as mitral annular plane systolic excursion (MAPSE).[5][6][7]

From 2009 to 2011, he was as a Post-doctoral Research Fellow in Cardiovascular MRI and CT at the National Institutes of Health (NIH) in Betheda, Maryland, USA. During this time he developed the use of myocardial T1 mapping by MRI to assess myocardial edema[8] and myocardial extracellular volume fraction (ECV).[9][10][11]

Between 2011 and 2019, he underwent clinical training in the physician specialty Clinical Physiology at Karolinska University Hospital in Stockholm, Sweden, where he also founded and led the Karolinska Cardiovascular Magnetic Resonance Group at the Karolinska Institutet. While at Karolinska, his team described the contribution of hydraulic forces to left ventricular diastolic filling[12], and developed Advanced ECG analysis methods for diagnosing heart disease.[13][14] This also included development of smartwatch 12-lead ECG.[15]

Since 2019, He is a Professor of Cardiac imaging and since 2020 Director of Clinical Imaging at the University of Sydney, leads the University of Sydney Cardiovascular Magnetic Resonance Research Group[16], and is founding convenor or the Sydney Clinical Imaging Network[17]. He is also founder of Advanced ECG Systems[18], a company formed to commercialize ECG research findings.

Since 2019, he is a fellow of the Cardiac Society of Australia and New Zealand (FCSANZ).[19]

Personal life

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He is married to Australian academic cardiologist Rebecca Kozor[20], and is the older brother of Swedish-American academic applied mathematician Johan Ugander.[21]

References

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  1. ^ European Society of Cardiology (ESC) 365. https://esc365.escardio.org/person/90250 Retrieved 27 March 2025.
  2. ^ Heart Research Australia Researchers. https://www.heartresearch.com.au/our-researchers/professor-martin-ugander/ Retrieved 27 March 2025.
  3. ^ University of Sydney Staff. https://www.sydney.edu.au/medicine-health/about/our-people/academic-staff/martin-ugander.html Retrieved 27 March 2025.
  4. ^ Ugander M, PhD thesis, Lund University, 2006. https://portal.research.lu.se/en/publications/dysfunctional-but-viable-myocardium-ischemic-heart-disease-assess
  5. ^ Carlsson M, Ugander M, Mosen H, Buhre T, Arheden H. Atrioventricular plane displacement is the major contributor to left ventricular pumping in healthy adults, athletes, and patients with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2007;292(3):H1452-1459. https://www.pubmed.gov/17098822
  6. ^ Carlsson M, Ugander M, Heiberg E, Arheden H. The quantitative relationship between longitudinal and radial function in left, right, and total heart pumpingin humans. Am J Physiol Heart Circ Physiol. 2007;293(1):H636-644. https://www.pubmed.gov/17307988
  7. ^ Ugander M, Carlsson M, Arheden H. Short-axis epicardial volume change is a measure of cardiac left ventricular short-axis function which is independent of myocardial wall thickness. Am J Physiol Heart Circ Physiol. 2010;298(2):H530-5. https://www.pubmed.gov/19933422
  8. ^ Ugander M, Bagi PS, Oki AJ, Chen B, Hsu LY, Aletras AH, Shah S, Greiser A, Kellman P, Arai AE. Myocardial edema as detected by pre-contrast T1 and T2 MRI delineates area at risk associated with acute myocardial infarction. JACC Cardiovasc Imaging. 2012. Jun, 5 (6) 596–603. https://www.pubmed.gov/22698528
  9. ^ Ugander M, Oki AJ, Hsu LY, et al. Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology. Eur Heart J. 2012;33(10):1268–1278. https://www.pubmed.gov/22279111
  10. ^ Moon JC, Messroghli DR, Kellman P, Piechnik SK, Robson MD, Ugander M, Gatehouse PD, Arai AE, Friedrich MG, Neubauer S, Schulz-Menger J, Schelbert EB. Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson. 2013 Oct 14;15:92. https://www.pubmed.gov/24124732
  11. ^ Messroghli DR, Moon JC, Ferreira VM, Grosse-Wortmann L, He T, Kellman P, Mascherbauer J, Nezafat R, Salerno M, Schelbert EB, Taylor AJ, Thompson R, Ugander M, van Heeswijk RB, Friedrich MG. Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI). J Cardiovasc Magn Reson. 2017 Oct 9;19(1):75. https://www.pubmed.gov/28992817
  12. ^ Maksuti E, Carlsson M, Arheden H, Kovács SJ, Broomé M, Ugander M. Hydraulic forces contribute to left ventricular diastolic filling. Sci Rep. 2017 Mar 3;7:43505. https://www.pubmed.gov/28256604
  13. ^ Hughes RK, Thornton GD, Malcolmson JW, Pierce I, Khoury S, Hornell A, Knott K, Captur G, Moon JC, Schlegel TT, Ugander M. Accurate diagnosis of apical hypertrophic cardiomyopathy using explainable advanced electrocardiogram analysis. Europace. 2024 Mar 30;26(4):euae093. https://www.pubmed.gov/38588067
  14. ^ Al-Falahi ZS, Schlegel TT, Palencia-Lamela I, Li A, Schelbert EB, Niklasson L, Maanja M, Lindow T, Ugander M. Advanced electrocardiography heart age: a prognostic, explainable machine learning approach applicable to sinus and non-sinus rhythms. Eur Heart J Digit Health. 2024 Oct 9;6(1):45-54. https://www.pubmed.gov/39846063
  15. ^ Ugander M, Curtis T. A method and a system for producing a standard 12-lead ECG. European Patent Office EP3973875B1. Granted 20 Dec 2023. https://patents.google.com/patent/EP3973875B1
  16. ^ University of Sydney Cardiovascular Magnetic Resonance Group. https://cmr.sydney.edu.au/ Retrieved 27 March 2025.
  17. ^ Sydney Clinical Imaging Network. https://scin.net.au/ Retrieved 27 March 2025.
  18. ^ Advanced ECG Systems https://www.aecgs.com Retrieved 27 March 2025.
  19. ^ Heart Research Australia Researchers. https://www.heartresearch.com.au/our-researchers/professor-martin-ugander/ Retrieved 27 March 2025.
  20. ^ McColl H, Chowdhury S, Schlegel TT, Maanja M, Yang K, Lindow T, Price M, Fulthorp E, Lal S, McGrady M, Kozor R, Ugander M. Diagnosing diastolic dysfunction using explainable advanced electrocardiography. medRxiv 2023.04.19.23288666. https://doi.org/10.1101/2023.04.19.23288666
  21. ^ Ugander J, PhD thesis, Cornell University, 2014. https://stanford.edu/~jugander/papers/jugander_phdthesis.pdf
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